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For Info Only.
Bob from Houston
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Date: Thu, 19 Mar 1998 13:55:04 -0500
Reply-To: Spinal Cord Injury Peer Net <scipin-l(AT)health.state.ny.us>
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From: Spinal Cord Injury Peer Net <scipin-l(AT)health.state.ny.us>
X-From: Maxim Bily <imax(AT)ODYSSEE.NET>
Subject: Human Body Manufactures 2 Nervous System Painkillers
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Human Body Manufactures 2 Nervous System Painkillers
Researchers have discovered two painkillers that are
produced naturally by
the body, a finding that might yield hints for
designing new medications to
treat a variety of painful conditions.
Such drugs might work against pain that does not
respond well to morphine,
such as some pain from cancer, from diabetic nerve
damage and from the
disease shingles.
Scientists have previously identified other natural
painkillers, called
endorphins, that act in the brain and spinal cord much
like morphine.
So far, the new painkillers have shown promise in
mice. One substance,
dubbed nocistatin (pronounced NO-suh-STAH-tin), is
described in today's
issue of Nature by Seiji Ito of the Kansai Medical
University in Osaka,
Japan, with colleagues there and elsewhere in Japan
and Singapore.
He and colleagues found the other new painkiller,
which they call OFQ2. A
report on their work is expected to appear in the
journal NeuroReport in a
couple weeks, he said.
Both painkillers are made from the same protein. Both
act on the central
nervous system, which includes the brain and spinal
cord.
) Copyright 1998 The Associated Press
-- Maksim (Max) Bilymail to: imax(AT)odyssee.net
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