The Use of Magnetic Resonance Spectroscopy and Cytokine Measurements to Investigate Depression in Autoimmune Neurologic Diseases

Johns Hopkins is currently enrolling TM, MS and non-autoimmune myelopathy patients in a prospective study (6 months follow-up) to investigate the epidemiology of cytokine-mediated depression and cognitive impairment in TM subjects compared to MS and non-autoimmune myelopathy controls.

Subjects will be followed longitudinally to determine if changes in cytokine levels and brain metabolites parallel changes in mood, cognition and neurologic outcomes.  Acute new onset TM and MS patients between the ages of 18-65 years will be enrolled in this study.

Interested patients should contact the study coordinator, Carrie Trecker, at 410-502-2574 for more information.

Principal Investigator: Adam Kaplin, MD/PhD
Registered Protocol Number: 03-07-03-09